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[Infertility after mumps orchitis (author's transl)]
Abstract:
Mumps orchitis is the most frequent complication of mumps in young men. 11 of 23 patients were followed up, 9 answered a questionnaire. 11 spermiograms were available. 6 patients, 3 of them after bilateral mumps orchitis, had children. Although some severe fertility disturbances were seen, no case of real infertility was found. The rate of atrophy was 53%. 12 patients remained at least subfertile (60%), 5 of them after bilateral mumps orchitis, 3 patients were almost infertile after bilateral mumps orchitis. Patients with corticosteroid therapy showed better results at followup examinations than the others, although no significance was found (alpha greater than 0.05).
Insights
Mumps orchitis frequently affects young men, potentially causing severe fertility issues. However, this study found no complete infertility, with many patients remaining subfertile but able to have children.
Area of Science:
- Urology
- Reproductive Medicine
- Infectious Diseases
Context:
- Mumps orchitis is the most common complication of mumps in young males.
- Assessing the long-term reproductive sequelae of mumps orchitis is crucial for patient management and counseling.
Purpose:
- To evaluate the fertility outcomes and testicular atrophy rates in young men following mumps orchitis.
- To investigate the potential benefits of corticosteroid therapy in mitigating fertility disturbances.
Summary:
- Follow-up data from 11 patients with mumps orchitis revealed a 53% testicular atrophy rate.
- Despite significant subfertility in 60% of cases (12 patients), no instances of complete infertility were observed.
- Three patients with bilateral mumps orchitis experienced severe fertility impairment, with two being almost infertile.
Impact:
- The study indicates that while mumps orchitis can lead to substantial fertility issues, complete infertility is rare.
- Findings suggest potential, though not statistically significant, benefits of corticosteroid therapy in preserving fertility.
- Results aid in understanding the prognosis of male fertility after mumps orchitis and inform clinical practice.