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Related Experiment Videos

Cyclical migraine.

J L Medina, S Diamond

    Archives of Neurology
    |June 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study observed cyclical migraine patterns in 27 patients, finding that lithium carbonate effectively controlled severe headaches in 19 out of 22 treated individuals.

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    Area of Science:

    • Neurology
    • Clinical Medicine

    Background:

    • Migraine headaches present with diverse symptoms and varying frequencies.
    • Cyclical patterns in migraine attacks are not fully understood.
    • Associated symptoms like nausea, vomiting, and photophobia are common.

    Purpose of the Study:

    • To investigate cyclical headache patterns in migraineurs.
    • To assess the efficacy of lithium carbonate in treating cyclical migraine.

    Main Methods:

    • Observation of 27 migraine patients with cyclical headache patterns.
    • Treatment of 22 patients with lithium carbonate.
    • Evaluation of headache severity, duration, and associated symptoms.

    Main Results:

    • Headaches occurred in cycles averaging six weeks, recurring five times annually.

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  • Severe migraines, lasting 25.5 hours on average, were frequent during cycles.
  • Lithium carbonate provided complete or partial headache control in 19 of 22 patients (86%).

    • Conclusions:

    • Migraine can manifest in distinct cyclical patterns.
    • Lithium carbonate demonstrates significant efficacy in managing cyclical migraine attacks.
    • Further research into lithium's mechanism in migraine is warranted.