[Histocytochemical features of immunopathologic changes in inflammation of the lungs]

The authors present the results of a comparative cytochemical study of the phagocytes' and lymphocytes' lysosomal membranes state in the rabbit blood, trachea and lungs in immunization with sorbed staphylococcus toxoid and human serum albumin in experimental pneumonia and in this disease against the background of immunization. It was shown that the changes resulting from immunization (the phagocytes' and lymphocytes' lysosomal membranes systemic destabilization, microcirculatory disorders, and cell infiltration in the lungs) were premorbid to pneumonia and intensified the inflammation. The authors considered these changes to be structural and functional signs of the immunopathological reactions accompanying pneumonia.