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Haloperidol secreted in breast milk.
British Medical Journal (Clinical Research Ed.)
|May 30, 1981
Summary
Haloperidol use during breastfeeding for postpartum psychosis appears safe for infants. Studies show no adverse effects on infant development, even with significant drug levels in breast milk.
Area of Science:
- Pharmacology
- Neonatal Health
- Psychiatry
Background:
- Puerperal psychosis is a severe postpartum mental health condition.
- Treatment often involves antipsychotic medications like haloperidol.
- Concerns exist regarding medication transfer to infants via breastfeeding.
Observation:
- A mother with puerperal psychosis received haloperidol 5 mg twice daily.
- She breastfed her infant under hospital supervision.
- Haloperidol levels in breast milk were measured up to 23.5 micrograms/l.
Findings:
- The breastfed infant showed no signs of sedation.
- The infant maintained good feeding habits.
- The infant demonstrated normal growth and development.
Implications:
- Short-term maternal haloperidol use may be compatible with breastfeeding.
- This suggests a potentially favorable risk-benefit balance for specific clinical scenarios.
- Further research is warranted to confirm long-term safety and efficacy.