[Concentration and purification of alkaline proteinase by ultrafiltration]

The mode of ultrafiltration of the culture fluid of Bacillus subtilis, producer of alkaline proteinase, through semipermeable acetate cellulose membranes was examined. The ultrafiltration of the enzyme-containing solutions involved both concentration of the solution and enzyme purification from low molecular weight admixtures. The optimum mode of ultrafiltration of alkaline proteinase on UAM membranes "Vladipore" was developed.