Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal necrotizing enterocolitis: a nine-year experience.

R M Kliegman, A A Fanaroff

    American Journal of Diseases of Children (1960)
    |July 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical trial of tin mesoporphyrin to prevent neonatal hyperbilirubinemia.

    Journal of perinatology : official journal of the California Perinatal Association·2016
    Same author

    Recent evidence based advances in neonatology.

    Early human development·2012
    Same author

    Effects of delayed cord clamping in very-low-birth-weight infants.

    Journal of perinatology : official journal of the California Perinatal Association·2011
    Same author

    To Phil Sunshine, MD, with admiration.

    Journal of perinatology : official journal of the California Perinatal Association·2011
    Same author

    Meconium aspiration syndrome: historical aspects.

    Journal of perinatology : official journal of the California Perinatal Association·2008
    Same author

    Association between early postnatal weight loss and death or BPD in small and appropriate for gestational age extremely low-birth-weight infants.

    Journal of perinatology : official journal of the California Perinatal Association·2007

    Necrotizing enterocolitis (NEC) outbreaks occurred periodically, affecting even low-risk infants and raising questions about its causes. Some cases arose during epidemics, suggesting infectious or environmental factors may play a role.

    Area of Science:

    • Neonatology
    • Pediatric Epidemiology
    • Gastroenterology

    Background:

    • Necrotizing enterocolitis (NEC) is a significant cause of morbidity and mortality in neonates.
    • Understanding the epidemiology of NEC is crucial for developing effective prevention and treatment strategies.

    Purpose of the Study:

    • To investigate the epidemiologic patterns of NEC over a nine-year period.
    • To identify potential risk factors and understand the timing and occurrence of NEC cases.

    Main Methods:

    • Retrospective review of 123 NEC cases over nine years.
    • Analysis of patient demographics, gestational age, birth weight, and presence of risk factors like umbilical artery catheters.
    • Examination of temporal clustering and epidemic patterns of NEC.

    Related Experiment Videos

    Main Results:

    • Mean gestational age was 31 weeks, mean birth weight 1,460 g; 7.3% were full-term and 10.5% small for gestational age.
    • No identifiable risk factor was found in 11.4% of cases, with some occurring during epidemics.
    • Clustering of cases was observed in 7 out of 108 months, and 13.8% of infants developed NEC after the third week of life.

    Conclusions:

    • The occurrence of NEC in low-risk patients and older neonates challenges current pathogenetic models.
    • Epidemic patterns suggest potential infectious or environmental triggers for NEC.
    • Further research is needed to elucidate the complex etiology of NEC.