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Updated: Aug 10, 2026
06:38
Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
Summary
High prolactin (PRL) impacts male reproductive function. This review covers PRL
Area of Science:
- Endocrinology
- Reproductive Medicine
- Men's Health
Background:
- Elevated prolactin (PRL) is linked to gonadal dysfunction in both sexes.
- The PRL-gonadal axis is well-defined in women, but less so in men.
Purpose of the Study:
- To review the influence of PRL on male reproductive function, even with normal PRL levels.
- To outline clinical, diagnostic, and therapeutic strategies for male hyperprolactinemia.
- To explore the connection between hyperprolactinemia and male sexual dysfunction/infertility.
Main Methods:
- Literature review of studies on prolactin and male reproductive health.
- Analysis of clinical data related to hyperprolactinemia in men.
- Synthesis of diagnostic and treatment approaches.
Main Results:
- Prolactin significantly influences male sexual function and fertility.
- Hyperprolactinemia presents with diverse clinical manifestations.
- Effective diagnostic and therapeutic protocols exist for managing this condition.
Conclusions:
- Understanding prolactin's role is crucial for male reproductive health.
- Prompt diagnosis and management of hyperprolactinemia improve outcomes.
- Further research can refine treatment strategies for male infertility and sexual dysfunction.
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