[Effect of calcitonin on human gastric function]

The effects of calcitonin on the gastric secretion have been investigated. Five subjects (age 34 and approximately 70 kg on average) have been injected by 0,25 microgram/kg s.c. a decrease of gastric secretion has been detected. The inhibition of pepsin secretion is much larger than the effect on MAO and PAO. This supports the hypothesis that calcitonin inhibits protein synthesis of the gastric mucous.