Chromosomal variants and male fertility

One hundred and forty-seven healthy men were investigated to determine whether there was an association between chromosomal variants and decreased fertility. Modern chromosome banding techniques detected normal variant karyotypes in 22 (15%) of these men. The fertility parameters of the 125 men with 46,XY karyotype were compared with those of the 22 men in the variant group. Analysis of the results showed that the two groups were not biologically different with respect to semen analysis and reproductive hormone levels.