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Congo/Crimean haemorrhagic fever in Iraq
Insights
Congo/Crimean hemorrhagic fever (CCHF) emerged in Iraq in 1979. Investigations revealed potential links to livestock and hospital-acquired infections, with virus isolates matching the CCHF group.
Area of Science:
- Virology
- Epidemiology
- Infectious Diseases
Background:
- Congo/Crimean hemorrhagic fever (CCHF) is a tick-borne viral disease.
- The disease was first identified in Iraq in 1979.
- Initial cases presented with potential links to animal contact and nosocomial transmission.
Purpose of the Study:
- To document the initial emergence and characteristics of CCHF in Iraq.
- To investigate the epidemiological links and transmission routes of early CCHF cases.
- To identify and characterize the causative viral agent.
Main Methods:
- Clinical case investigation and patient interviews.
- Virus isolation from blood and postmortem liver specimens.
- Serological analysis of virus isolates.
Main Results:
- Ten CCHF cases were investigated starting September 1979.
- Eight patients reported contact with sheep or cattle.
- Two healthcare workers acquired infections nosocomially.
- Virus isolates were closely related to the CCHF virus group.
- Cases were geographically dispersed around Baghdad and Ramadi.
Conclusions:
- The study confirmed the presence of CCHF virus in Iraq.
- Evidence suggested both zoonotic and nosocomial transmission pathways.
- The geographically dispersed nature of early cases indicated potential for wider spread.
Abstract:
Congo/Crimean haemorrhagic fever was recognized for the first time in Iraq in 1979. The first case was reported on 3 September 1979 and since then a further 9 patients have been investigated. Eight patients gave a history of previous contact with sheep or cattle, while 2 patients, a resident doctor and an auxiliary nurse, acquired their infections in hospital by direct contact with patients. The causal virus was isolated from patients' blood and postmortem liver specimens. The virus isolates were found to be closely related if not identical serologically to members of the Congo/Crimean haemorrhagic fever virus group. Eight of the patients had no epidemiological relationship to one another and lived in widely separated areas around Baghdad and Ramadi (110 km to the west of Baghdad).
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