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[Standardized postoperative parenteral nutrition with a complete solution containing glucose].

W Behrendt, C Classen

    Infusionstherapie Und Klinische Ernahrung
    |June 1, 1981
    PubMed
    Summary

    This study found that a new intravenous solution containing amino acids and dextrose is safe for post-cholecystectomy patients. The nutritional support effectively managed blood glucose and nitrogen balance without significant side effects.

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    Area of Science:

    • Clinical Nutrition
    • Metabolic Studies
    • Postoperative Care

    Context:

    • Postoperative recovery after cholecystectomy often requires nutritional support.
    • Peripheral vein administration of intravenous solutions presents challenges in osmolarity and patient tolerance.
    • Optimizing nutritional delivery is crucial for patient outcomes.

    Purpose:

    • To evaluate the efficacy and safety of a novel intravenous solution for nutritional support in cholecystectomized patients.
    • To assess metabolic parameters including blood glucose, glucose excretion, and nitrogen balance.
    • To determine the tolerability of the solution administered via peripheral veins.

    Summary:

    • Fifteen cholecystectomized patients received a new intravenous solution (2% amino acids, 12.5% dextrose, electrolytes) for 3 days.

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  • The solution, with an osmolarity of 1.060 mosmol/l, was administered peripherally, maintaining blood glucose below 8.8 mmol/l.
  • No insulin or extra potassium was needed; glucose excretion was 3.3-7.6%, nitrogen excretion averaged 8.4 g/day, and nitrogen balance was -2.6 g/day.

    • Impact:

    • The tested solution demonstrates safe and effective nutritional support in the early postoperative period.
    • Peripheral administration is feasible, though minor vein irritation was noted in some cases.
    • Findings support the use of this solution to improve postoperative recovery and nutritional status.