[Comparative study of different methods of determining ovalbumin in preparations of purified influenza virus]

The degree of purity of inactivated influenza vaccines was assayed in the anaphylaxis test in guinea pigs as well as by the values of total protein and ovalbumin measured by IHA and ID tests. Quantitation of ovalbumin in vaccines by the IHA test with an antiovalbumin diagnostic preparation was found to be most informative, rapid and highly sensitive. This method may be recommended for quantitation of ovalbumin impurities in samples of purified influenza virus obtained by different methods and for different purposes.