[CLearance of Pseudomonas aeruginosa from the lungs in experimental burn trauma]

Experiments carried out in rats demonstrated that a burn of degree III of 20% of the body surface disturbs considerably the process of lung clearance from bacterial dissemination (5 million bodies of Pseudomonas pyocyanea). Not only decreased but even negative clearance may be observed indicating multiplication of the bacteria in pulmonary tissues for the first 3 days after burn, and intratracheal infection of the animals. Reduced general antibacterial resistance as a result of burn facilitates rapid penetration of P. pyocyanea into the lymph nodes, blood, kidneys, liver, spleen where it is found 6 hours after infection.