Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sperm shape abnormalities in carbaryl-exposed employees.

A J Wyrobek, G Watchmaker, L Gordon

    Environmental Health Perspectives
    |August 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Low dose radiation response curves, networks and pathways in human lymphoblastoid cells exposed from 1 to 10cGy of acute gamma radiation.

    Mutation research·2011
    Same author

    The use of economic evaluations in NHS decision-making: a review and empirical investigation.

    Health technology assessment (Winchester, England)·2008
    Same author

    Recruiting staff--a short guide for GPs and private consultants.

    Irish medical journal·2008
    Same author

    The association of folate, zinc and antioxidant intake with sperm aneuploidy in healthy non-smoking men.

    Human reproduction (Oxford, England)·2008
    Same author

    Supra-elevated CA 19-9 in a benign hepatic cyst adenoma.

    HPB : the official journal of the International Hepato Pancreato Biliary Association·2008
    Same author

    Optimisation of circulating biomarkers of cell death for routine clinical use.

    Annals of oncology : official journal of the European Society for Medical Oncology·2008

    Occupational exposure to carbaryl (1-naphthyl methyl carbamate) was linked to increased sperm abnormalities in production workers. Further research is needed to confirm a definitive link and explore reversibility and other workplace factors.

    Area of Science:

    • Occupational Health
    • Reproductive Toxicology
    • Environmental Health

    Background:

    • Carbaryl (1-naphthyl methyl carbamate) is an insecticide used in various applications.
    • Occupational exposure to pesticides may pose risks to reproductive health.
    • Understanding the impact of carbaryl exposure on human semen quality is crucial for worker safety.

    Purpose of the Study:

    • To investigate the effects of occupational carbaryl exposure on semen parameters in production plant workers.
    • To assess potential links between carbaryl exposure duration and sperm count, morphology, and YFF frequency.
    • To explore the reversibility of observed seminal defects after cessation of exposure.

    Main Methods:

    • Semen samples were collected from 50 occupationally carbaryl-exposed men and 34 unexposed controls.

    Related Experiment Videos

  • Semen analysis included sperm count, morphology, and frequency of sperm carrying double fluorescent bodies (YFF).
  • Data on employment, fertility, health, and personal habits were collected for each participant.

    • Main Results:

    • Exposed workers showed a significantly higher proportion of sperm with abnormal head shapes compared to controls (p < 0.005).
    • No significant differences were observed in sperm count or YFF frequency between groups.
    • Formerly exposed workers exhibited a marginally significant increase in sperm abnormalities, suggesting potential non-reversibility.

    Conclusions:

    • Carbaryl exposure in production workers is associated with increased sperm morphology abnormalities.
    • The observed abnormalities were not dose-dependent and appeared primarily in workers with less than 6 years of exposure.
    • A definitive link between carbaryl and human seminal defects cannot be established; further research is needed to explore confounding factors and reversibility.