The use of a computer in parenteral alimentation of low birth weight infants

A computer program which aids in the formulation and preparation of parenteral nutrition fluids for low birth weight infants is described. The program performs a number of calculations for fluid and specific nutrient requirements taking into account environmental conditions, potential renal solute load, deficits, and surpluses. Safety and precipiation checks are also included in the calculations. Its use has considerably reduced the workload on both physician and pharmacy personnel involved in the formulation and preparation of individualized parenteral nutrition solutions for low birth weight infants. A controlled study in 15 very low birth weight infants utilizing this program revealed a reduced incidence of hyperglycemia, decrease in fluctuations in serum sodium, a more physiologic urine osmolality, and a reduction of weight loss in the first days of life.