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Related Experiment Videos

[Calcium desorption from the cornea while using complex-forming substances].

T V Velikova, I V Kolosov, O S Komarov

    Biulleten' Eksperimental'Noi Biologii I Meditsiny
    |September 1, 1981
    PubMed
    Summary

    Calcium can be actively absorbed by the cornea, causing cloudiness. Complex-forming substances combined with papain effectively remove calcium, potentially avoiding corneal surgery.

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    Area of Science:

    • Ophthalmology
    • Biochemistry
    • Materials Science

    Context:

    • Corneal opacity is a significant cause of visual impairment.
    • Calcium deposition in the cornea can lead to pathological changes and vision loss.
    • Current treatments for corneal opacity often involve invasive surgical procedures.

    Purpose:

    • To investigate the kinetics of calcium desorption from the cornea.
    • To evaluate the efficacy of complex-forming agents in calcium removal.
    • To explore non-surgical therapeutic strategies for corneal calcification.

    Summary:

    • Experiments utilizing labeled calcium demonstrated active absorption by the normal cornea, resulting in turbidity.
    • The removal of calcium from isolated corneas and corneal tissues was enhanced by combining complex-forming substances with papain, a diffusion facilitator.

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  • This combined approach led to a reduction in corneal tissue turbidity.

    • Impact:

    • The findings suggest a potential non-surgical method for managing corneal calcification.
    • This approach may reduce the need for corneal transplantation or other surgical interventions.
    • Further research could lead to novel therapeutic agents for treating corneal opacities caused by calcium deposition.