Brucella mellitensis endocarditis on a porcine heterograft bioprosthesis

A Brucella mellitensis endocarditis on a Hancock valve bioprosthesis is reported. The patient was successfully treated by a combination of valve replacement, wide surgical debridement of the aortic annulus and medical treatment with trimethoprim and sulfamethoxazole. To the best of our knowledge, this is the first case of Brucella endocarditis on a bioprosthesis.