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Related Experiment Videos

The pathologic implication of duodenal diverticula.

A Eggert, W Teichmann, D H Wittmann

    Surgery, Gynecology & Obstetrics
    |January 1, 1982
    PubMed
    Summary

    Duodenal diverticula increase the risk of bacteriocholia (bacteria in bile), particularly near the papilla of Vater. This complication may contribute to biliary tract disease and pancreatitis.

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    Area of Science:

    • Gastroenterology
    • Hepatology
    • Biliary tract disease

    Background:

    • Duodenal diverticula are outpouchings in the duodenum.
    • Calculous biliary tract disease involves gallstones and inflammation.
    • Bacteriocholia, bacteria in bile, is a known complication.

    Purpose of the Study:

    • To investigate the prevalence of bacteriocholia in patients with duodenal diverticula and calculous biliary tract disease.
    • To determine the relationship between duodenal diverticula location and bacteriocholia.
    • To assess the impact of age on bacteriocholia in this patient group.

    Main Methods:

    • Prospective study design.
    • Inclusion of 80 patients with duodenal diverticula and calculous biliary tract disease.
    • Comparison with patients having cholelithiasis without duodenal diverticula.

    Main Results:

    • Bacteriocholia was found in 51/71 patients with duodenal diverticula versus 278/809 without.
    • Bacteriocholia rates decreased with increasing distance between diverticula and the papilla of Vater.
    • Older age correlated with increased rates of bacteriocholia.

    Conclusions:

    • Duodenal diverticula are associated with a higher incidence of bacteriocholia.
    • Juxtapapillary duodenal diverticula appear to be a significant pathogenic factor for biliary tract inflammation and pancreatitis.
    • The clinical significance of juxtapapillary duodenal diverticula may be underestimated.

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