[Prevention of external respiratory and gas exchange disorders in patients postoperatively]

The investigation of oxygen exchange in 70 patients operated on the organs of the abdominal cavity has shown that pronounced disturbances of the function of external ventilation and gas exchange are developing in patients in the postoperative period. The application of prolonged ganglionic blockade with normotony by pentamine both during operation and within 5 postoperative days promoted the improvement of oxygen exchange at the level of lungs and tissues. The authors believe that it prevents hyperreaction of the sympatho-adrenal system and adrenals upon the operation trauma, disturbances of the blood microcirculation and the development of metabolic alkalosis in the postoperative period.