Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteopenia in juvenile diabetes.

R M Shore, R W Chesney, R B Mazess

    Calcified Tissue International
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Malignant melanoma of the vulva: an extension of cutaneous melanoma?

    Gynecologic oncology·2011
    Same author

    Concurrent chemoradiation for locally advanced carcinoma of the cervix: where are we in 2006?

    Annals of oncology : official journal of the European Society for Medical Oncology·2006
    Same author

    Second-look operation improves survival in suboptimal, debulked, stage III ovarian cancer.

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2005
    Same author

    Gemcitabine reverses platinum resistance in platinum-resistant ovarian and peritoneal carcinoma.

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2005
    Same author

    A review of intravenous versus oral vitamin D hormone therapy in hemodialysis patients.

    Clinical nephrology·2003
    Same author

    Chemoradiotherapy for cervical cancer.

    European journal of cancer (Oxford, England : 1990)·2002

    Children with diabetes mellitus exhibit lower bone mineral content, regardless of disease duration. Higher insulin doses were observed in children with reduced bone density, indicating a potential link between diabetes management and bone health in pediatric patients.

    Area of Science:

    • Pediatric Endocrinology
    • Metabolic Bone Disease
    • Diabetes Mellitus Research

    Background:

    • Diabetes mellitus can affect bone metabolism.
    • Osteopenia is a concern in children with chronic diseases.
    • Understanding bone mineral status in pediatric diabetes is crucial.

    Purpose of the Study:

    • To assess bone mineral status in children with diabetes mellitus.
    • To investigate factors associated with bone demineralization in this population.
    • To evaluate the relationship between diabetes duration, insulin dosage, and bone density.

    Main Methods:

    • Single photon absorptiometry was used to measure bone mineral content.
    • Bone mineral content was compared to age, sex, height, and weight-predicted values.

    Related Experiment Videos

  • Data on diabetes duration, insulin dose, growth, renal function, and serum calcium/phosphorus were collected.

    • Main Results:

    • Children with diabetes had 13% lower mean bone mineral content than predicted.
    • Osteopenia was present even in children with diabetes duration of one year or less.
    • Demineralized children received higher daily insulin doses; no associations with sex, growth, renal function, or serum minerals were found.

    Conclusions:

    • Children with diabetes mellitus frequently present with reduced bone mineral content.
    • Early-onset diabetes does not appear to mitigate osteopenia risk.
    • Higher insulin requirements may be linked to decreased bone mineral density in pediatric diabetes.