Related Experiment Video
Updated: Aug 18, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
Cytological changes of the conjunctiva in immunoglobulin-producing dyscrasias
Abstract:
The conjunctivae of 15 patients with confirmed immunoglobulin-producing dyscrasias were examined by cytological techniques. Of 13 patients with no gross ocular symptoms, 10 showed distinct epithelial cell changes and/or the presence of periodic acid-Schiff (PAS)-positive cells. Two other patients with gross abnormalities of the conjunctiva revealed the presence of PAS-positive cells, Dutcher bodies, and lymphocytoid-plasma cells. Lymphomatous deposition may develop in the conjunctiva and present as conjunctival nodules or as a diffuse infiltration. It is concluded that the cytological preparation of conjunctival smears may serve as a sensitive indicator of systemic immunoglobulin-producing dyscrasias.
Related Concept Videos
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Immunoglobulin-like Cell Adhesion Molecules
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
Immunocytochemistry and Immunohistochemistry
These...
Microbiome of the Eye
Cytomegalovirus Disease

