[Infections by group D streptococci (author's transl)]

Area of Science:

• Pediatric Infectious Diseases
• Neonatal Infections
• Bacteriology

Context:

• Study conducted at the Pediatric Department of the School of Medicine at Barcelona.
• Analyzed 20 cases of newborn sepsis and 9 urinary tract infections in children.
• Identified Group D streptococci, specifically enterococci, as the causative agents.

Purpose:

• To investigate pediatric infections caused by Group D streptococci.
• To determine antibiotic sensitivities of isolated enterococci strains.
• To evaluate clinical presentation, treatment outcomes, and prognosis.

Summary:

• Neonatal sepsis occurred early in 50% of cases, with 35% low birth weight infants; 95% had favorable outcomes, except for one meningitis case.
• Urinary tract infections were most common in infants over one month old (44%), presenting with mild symptoms and responding well to antibiotics.
• Isolated enterococci showed highest sensitivity to ampicillin, followed by carbenicillin, chloramphenicol, furantoin, and gentamicin.

Impact:

• Highlights the effectiveness of antibiotics like ampicillin in treating enterococcal infections in children.
• Underscores the significant long-term risk of renal and urinary malformations (55% of patients), impacting prognosis.
• Provides crucial data for managing pediatric Group D streptococcal infections and associated congenital anomalies.