Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Convulsion in the aged.

E Otomo

    Folia Psychiatrica Et Neurologica Japonica
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study found that 4% of older adults experienced convulsions, with a higher incidence in those with cerebrovascular disorders. Epilepsy was rare, and specific electroencephalographic patterns were uncommon in this age group.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cilostazol stroke prevention study: A placebo-controlled double-blind trial for secondary prevention of cerebral infarction.

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2013
    Same author

    Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy.

    Journal of neurology, neurosurgery, and psychiatry·2005
    Same author

    Association of neprilysin polymorphism with cerebral amyloid angiopathy.

    Journal of neurology, neurosurgery, and psychiatry·2003
    Same author

    No association of paraoxonase genotype or atherosclerosis with cerebral amyloid angiopathy.

    Stroke·2002
    Same author

    Lack of association of neprilysin polymorphism with Alzheimer's disease and Alzheimer's disease-type neuropathological changes.

    Journal of neurology, neurosurgery, and psychiatry·2002
    Same author

    Very early onset Alzheimer's disease with spastic paraparesis associated with a novel presenilin 1 mutation (Phe237Ile).

    Journal of neurology, neurosurgery, and psychiatry·2001

    Area of Science:

    • Neurology
    • Geriatrics
    • Pathology

    Background:

    • Convulsions and electroencephalographic (EEG) patterns are critical indicators of neurological health, particularly in aging populations.
    • Understanding the incidence and causes of seizures in older adults is essential for effective clinical management and prognosis.

    Purpose of the Study:

    • To investigate the prevalence of convulsions and specific EEG findings in individuals aged 60 and over.
    • To determine the association between cerebrovascular disorders, brain tumors, and convulsive episodes in the elderly.
    • To analyze the incidence of typical spike-and-wave complexes and other EEG abnormalities in this demographic.

    Main Methods:

    • Retrospective analysis of clinical data and autopsy findings from 2,625 subjects aged 60+.

    Related Experiment Videos

  • Examination of EEG records from 20,000 individuals.
  • Specific focus on 72 cases with cerebrovascular disorders and 30 cases with brain tumors.

    • Main Results:

    • Convulsions were observed in 4% of the total cohort, with epilepsy noted in 0.076%.
    • A significant increase in convulsion incidence (26.4%) was found in recent cases of cerebrovascular disorders, particularly during acute cerebral apoplexy, with myoclonus being the most common manifestation.
    • Convulsions occurred in 13.3% of patients with brain tumors. Typical spike-and-wave complexes on EEG were rare (<0.005%), and no 6 and 14c/sec positive spikes were identified.

    Conclusions:

    • Cerebrovascular disorders, especially acute cerebral apoplexy, are significant contributors to convulsive seizures in the elderly, often with a poor prognosis.
    • The incidence of epilepsy is low in this age group, and specific EEG abnormalities like typical spike-and-wave complexes are infrequent.
    • Further research into the mechanisms and management of seizures in elderly patients with neurological conditions is warranted.