Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Matrix program to analyze primary structure homology.

J Novotny

    Nucleic Acids Research
    |January 11, 1982
    PubMed
    Summary
    This summary is machine-generated.

    A new FORTRAN program analyzes sequence homology using dot matrix displays. This user-friendly tool enhances analysis with filtering, fudging, and screening options for nucleotide and amino acid sequences.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Gastric pH and Fusobacterium gastrosuis detection in relation to gastric lesions in fattening pigs.

    Polish journal of veterinary sciences·2026
    Same author

    Observation of Radially Emitted Proton Beams from Low-Mass X-Pinch Plasmas.

    Physical review letters·2026
    Same author

    Contemporary insights and evolving clinical pathways in transcatheter tricuspid valve replacement.

    Herz·2026
    Same author

    The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024).

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2024
    Same author

    The guidelines for clinical practice for carriers of germline mutations in hereditary breast, ovarian, prostate, and pancreatic cancer predisposition genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 (4.2024).

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2024
    Same author

    Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat.

    Physiological research·2022
    Same journal

    Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

    Nucleic acids research·2026
    Same journal

    VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

    Nucleic acids research·2026
    Same journal

    Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

    Nucleic acids research·2026
    Same journal

    Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

    Nucleic acids research·2026
    Same journal

    Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

    Nucleic acids research·2026
    Same journal

    Correction to 'The Gene Ontology knowledgebase in 2026'.

    Nucleic acids research·2026
    See all related articles

    Area of Science:

    • Bioinformatics
    • Computational Biology
    • Genomics

    Background:

    • Homology analysis is crucial for understanding biological sequences.
    • Existing methods may lack user-friendliness or analytical flexibility.

    Purpose of the Study:

    • To present a FORTRAN program for analyzing letter string homology.
    • To provide a user-friendly tool with enhanced analytical capabilities for sequence comparison.

    Main Methods:

    • Development of a FORTRAN program for sequence homology analysis.
    • Implementation of dot matrix visualization for results.
    • Inclusion of options for filtering, fudging (homologous residue groups), and screening (specific residue groups).

    Main Results:

    Related Experiment Videos

    • The program successfully analyzes homology of nucleotide and amino acid sequences.
    • Dot matrix displays effectively visualize homology.
    • Options for filtering, fudging, and screening significantly increase analytical power.

    Conclusions:

    • The presented FORTRAN program offers a powerful and user-friendly approach to sequence homology analysis.
    • The program's options enhance its utility for researchers in bioinformatics and related fields.