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[Effect of hypokinesia on bone tumor induction]
Voprosy Onkologii
|January 1, 1982
Abstract:
The effects of different periods of hypokinesia on the development of 7.12-dimethyl-benzoanthracene-induced osteosarcoma of shinbone were studied in 148 rabbits. The time of induction was found to decrease considerably - from 197.6 to 113.9 days. This may be attributed to hypokinesia's constituting a stress, which involves release of adrenocortical hormones, atrophy of the thymus and reduced cellular immunological vigor.