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Related Experiment Videos

Side effects of benoxaprofen.

C Hindson, T Daymond, B Diffey

    British Medical Journal (Clinical Research Ed.)
    |May 8, 1982
    PubMed
    Summary
    This summary is machine-generated.

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    Benoxaprofen, a non-steroidal anti-inflammatory drug, caused various adverse skin reactions including photosensitivity and severe conditions like Stevens-Johnson syndrome. These findings highlight potential risks associated with benoxaprofen use.

    Area of Science:

    • Dermatology
    • Pharmacology

    Background:

    • Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for pain and inflammation.
    • Benoxaprofen is an NSAID with known side effects.

    Purpose of the Study:

    • To investigate and document the adverse dermatological reactions associated with benoxaprofen use.
    • To characterize the nature and severity of these cutaneous side effects.

    Main Methods:

    • Observational study of patients experiencing side effects.
    • Clinical assessment of dermatological reactions.
    • Analysis of reaction patterns and severity.

    Main Results:

    • Photosensitivity reactions were observed, primarily at wavelengths below 340 nm.

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  • Other reported side effects included erythema multiforme, Stevens-Johnson syndrome, milia, and onycholysis.
  • One severe case involved pancytopenia and toxic epidermal necrolysis.

    • Conclusions:

    • Benoxaprofen is associated with a range of adverse dermatological reactions.
    • The observed reactions, including photosensitivity and severe cutaneous events, are likely true side effects of the drug.