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[Ultrastructure and cytochemistry of primordial germ cells involved in migration in dichlorvos-treated quail embryos]
Comptes Rendus Des Seances De L'Academie Des Sciences. Serie III, Sciences De La Vie
|December 21, 1981
Abstract:
In dichlorvos-treated quail embryos, the ultrastructural cytochemistry of gonads reveals perturbations in the glycoconjugate distribution. The modifications observed concern the surface and matricial glycoconjugates of tissues involved in the primordial germ cells (PGC) migration. In treated embryos, these cytochemical alterations could explain a delayed migration of PGC to germinal anlage and their disturbed settling into gonads.
Insights
Dichlorvos exposure alters gonad glycoconjugates in quail embryos, potentially delaying primordial germ cell migration and settlement. These changes impact early gonad development.
Area of Science:
- Developmental biology
- Toxicology
- Cell biology
Context:
- Quail embryos exposed to the insecticide dichlorvos.
- Focus on the ultrastructural and cytochemical analysis of gonads.
Purpose:
- To investigate the effects of dichlorvos on gonad development at the ultrastructural level.
- To examine alterations in glycoconjugate distribution within quail gonads following dichlorvos exposure.
Summary:
- Dichlorvos exposure caused significant changes in glycoconjugate distribution in quail embryo gonads.
- These modifications were observed in both surface and matrix glycoconjugates of tissues crucial for primordial germ cell (PGC) migration.
- The observed cytochemical alterations may lead to delayed PGC migration and improper settling within the developing gonads.
Impact:
- Provides insights into the mechanisms by which organophosphate pesticides like dichlorvos can disrupt reproductive development.
- Highlights the role of glycoconjugates in guiding germ cell migration and gonad formation.
- Suggests potential risks of dichlorvos exposure to avian reproductive health and population dynamics.