Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diminished hypercapnic drive in endogenous or severe depression.

J Damas-Mora, L Souster, F A Jenner

    Journal of Psychosomatic Research
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Letters to and from the editor.

    Perspectives in biology and medicine·2015
    Same author

    Chairman's Summing Up.

    Proceedings of the Royal Society of Medicine·2010
    Same author

    Users' satisfaction with mental health services.

    The International journal of social psychiatry·1993
    Same author

    Attitudes of professional mental health workers to psychiatry.

    The International journal of social psychiatry·1993
    Same author

    Mentally abnormal homicide--a review of a special hospital male population.

    Medicine, science, and the law·1993
    Same author

    Patterns of benzodiazepine use in Great Britain as measured by a general population survey.

    The British journal of psychiatry : the journal of mental science·1989
    Same journal

    Association of kynurenine metabolites with cognitive and psychological symptoms in post COVID-19 condition: A case-control study.

    Journal of psychosomatic research·2026
    Same journal

    Applying the functional somatic disorder classification to somatic symptom disorder: Findings from the SOMA.SSD study.

    Journal of psychosomatic research·2026
    Same journal

    Psychological and medical outcomes of post-COVID-19 patients: A longitudinal study.

    Journal of psychosomatic research·2026
    Same journal

    Beyond general depression: Premenstrual interpersonal anger as a unique pathway to suicidal ideation in adolescent females with ADHD.

    Journal of psychosomatic research·2026
    Same journal

    Function-based reorganization of general hospital psychiatry in Japan: A perspective.

    Journal of psychosomatic research·2026
    Same journal

    Metabolic and psychiatric changes after laparoscopic sleeve gastrectomy in patients with mood disorders and metabolic syndrome.

    Journal of psychosomatic research·2026
    See all related articles

    Patients with primary depression exhibit faster resting breathing rates and lower end-tidal PCO2 levels. Their ventilatory response to carbon dioxide (CO2) correlates with depression severity, particularly in endogenous subtypes.

    Area of Science:

    • Respiratory Physiology
    • Clinical Psychology
    • Psychiatry

    Background:

    • Primary depression is associated with various physiological changes.
    • Understanding respiratory patterns in depression is crucial for diagnosis and treatment.
    • Previous research suggests potential links between breathing regulation and mood disorders.

    Purpose of the Study:

    • To investigate resting breathing rate, end-tidal PCO2, and ventilatory response to CO2 in primary depression patients.
    • To compare these respiratory parameters between depressed patients and control subjects.
    • To explore the relationship between CO2 response and depression severity and subtypes.

    Main Methods:

    • Studied resting breathing rate and resting end-tidal PCO2.
    • Assessed ventilatory response to CO2 using a modified Read rebreathing technique.

    Related Experiment Videos

  • Correlated CO2 response with depression severity and classified patients into endogenous and reactive subtypes.

    • Main Results:

    • Patients with primary depression showed significantly faster resting breathing rates and lower resting end-tidal PCO2 compared to controls.
    • Endogenous depressives exhibited lower CO2 responses and thresholds than reactive depressives.
    • A strong correlation was found between CO2 response on admission and the severity of depression.

    Conclusions:

    • Altered resting breathing patterns and blunted ventilatory responses to CO2 are characteristic of primary depression.
    • CO2 response may serve as a potential biomarker for depression severity.
    • The findings highlight the interplay between respiratory control and depressive states, with distinct patterns observed in different depression subtypes.