Oral mannitol as a preparation for double contrast barium enema

A oral mannitol purgative which is used prior to colonoscopy proved disappointing for barium enema preparation. A number of ways of improving bowel clearance with mannitol in divided dosage, preliminary oral metoclopramide and a clear fluid diet have been assessed. Divided dosage and a clear fluid diet were both beneficial, whereas oral metoclopramide was ineffective. Using the best regime, 38% of patients had a totally clear bowel compared with 33% using an established lavage technique. It is concluded that oral mannitol, with a clear fluid diet, is a satisfactory preparation for double contrast barium enema, and a regime is recommended.