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The effect of chlorpromazine on transformation in Bacillus subtilis
Molecular & General Genetics : MGG
|January 1, 1982
Abstract:
In the presence of the widely used tranquilizer, chlorpromazine, transforming DNA of Bacillus subtilis is photoinactivated by long-wave ultraviolet light. The loss of biological activity is predominantly caused by lack of binding of the DNA to recipient cells and the introduction of single-strand breaks in the treated DNA.