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Updated: Aug 18, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
11:39

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

[Test-provoked correlations between regional intracranial blood volume and intracranial pressure in infants during

D Bilz, A Pásztor, E Paraicz

    Psychiatrie, Neurologie, Und Medizinische Psychologie
    |August 1, 1981
    PubMed

    Insights

    This study in infants with severe conditions used provocation tests to measure intracranial blood volume (rICBV) and intracranial pressure (ICP). Simultaneous measurements help identify pathological ICP increases and reactive hyperemia, crucial for patient management.

    Area of Science:

    • Pediatric Neurology
    • Neurocritical Care
    • Cerebrovascular Physiology

    Context:

    • Clinical study involving five infants with severe medical conditions.
    • Simultaneous recording of intracranial blood volume (rICBV) and intracranial pressure (ICP) was performed.
    • Utilized various provocation tests to assess physiological responses.

    Purpose:

    • To investigate the relationship between rICBV and ICP under provocative conditions.
    • To establish a theoretical basis for the cerebrospinal fluid volume/pressure response.
    • To identify critical ICP thresholds indicative of pathological increases.

    Summary:

    • Provocation tests were used during simultaneous rICBV and ICP measurements in infants.
    • Hydrostatic pressure tests provided insights into cerebrospinal fluid dynamics.
    • Differentiated appraisal of critical ICP points was achieved, highlighting reactive hyperemia.

    Impact:

    • Informs the understanding of intracranial volume-pressure dynamics in critically ill infants.
    • Aids in the precise identification of pathological intracranial pressure.
    • Emphasizes the importance of managing reactive hyperemia for improved outcomes.

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