[Comparison of adsorption capacity for FSH between kaolin and montmorillonite. Biological and immunological activity...

The adsorption capacity of urinary FSH has been studied comparatively with kaolin and montmorillonite, a new type of bentonite, never used before in gonadotrophin adsorption. To measure adsorption capacity, two different assay methods were used: bioassay (for biological activity of the kaolin and montmorillonite extracts) and radioimmunoassay (RIA) for the immunological activity of FSH in both extracts. From the present results a biological activity increase was observed in montmorillonite extracts, while no significant differences between immunological activity of FSH were found in either extract. These findings suggest that montmorillonite could replace kaolin in gonadotrophins extraction and purification methods.