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The effects of ampicillin on oral contraceptive steroids in women
British Journal of Clinical Pharmacology
|July 1, 1982
Abstract:
1 Thirteen women taking long term oral contraceptive steroids were studied while taking ampicillin (500 mg three times daily) and compared to a control cycle while not taking ampicillin. 2 There were no significant changes in the plasma concentrations of ethinyloestradiol, levonorgestrel, follicle stimulating hormone or progesterone, although lower concentrations of ethinyloestradiol were noted in two women. 3 We conclude that most patients taking oral contraceptive steroids do not need to take alternative contraceptive precautions while taking ampicillin.
Keywords:
BiologyContraceptionContraceptive Agents, Estrogen--analysisContraceptive Agents, Female--analysisContraceptive Agents, Progestin--analysisContraceptive Agents--analysisControl GroupsEndocrine SystemEstrogensEthinyl Estradiol--analysisFamily PlanningFollicle Stimulating Hormone--analysisGonadotropinsGonadotropins, PituitaryHormonesLevonorgestrel--analysisNorethindrone AcetatePhysiologyPregnancy, UnplannedProgestational HormonesProgesterone--analysisReproductive Control AgentsResearch Methodology