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Related Experiment Videos

Cross-reactivity between grass and corn pollen antigens.

K J Kalveram, G Forck

    International Archives of Allergy and Applied Immunology
    |January 1, 1978
    PubMed
    Summary

    Grass and corn pollen allergies may share common allergens. Research suggests grass pollen extract can detect corn pollen allergens, potentially simplifying diagnosis and treatment for combined allergies.

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    Area of Science:

    • Allergy and Immunology
    • Immunochemistry

    Background:

    • Patients with pollinosis exhibit similar skin test reactions to grass and corn pollen extracts.
    • This suggests a potential antigenic relationship between these pollen types.

    Purpose of the Study:

    • To investigate the antigenic relationship between grass and corn pollens using the RAST inhibition test.
    • To determine if grass pollen extract can be used for diagnosing combined grass and corn pollen allergies.

    Main Methods:

    • Utilized the RAST inhibition test.
    • Employed cellulose discs labeled with commercial skin test extracts of various pollens including grass, rye, wheat, barley, oat, and maize (corn).

    Main Results:

    • Mutual inhibition tests revealed varying degrees of antigenic relationships between the pollens.
    • Grass pollen antigens demonstrated a strong ability to inhibit antigen-antibody reactions involving other tested pollens, including corn pollen.

    Conclusions:

    • The study suggests that grass pollen extract contains antigens common to corn pollen.
    • This finding supports the potential use of a single grass pollen extract for the diagnosis and possibly therapy of combined grass and corn pollen allergy.

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