[Therapy of leg ulcers with disodium cromoglycate (DNCG)--case reports ]

For the first time in Germany DNCG was tested in a pilot study for local treatment in ten patients (nine with chronic venous insufficiency, one with an arterio-venous insufficiency) with leg ulcers. Complete healing was achieved in three patients. One of these patients was the above mentioned with the combined arterio-venous insufficiency. Another four patients with larger ulcers showed marked ulcer decrease on treatment. DNCG was generally well tolerated. Due to local irritations the drug had to be withdrawn in three patients. On account of these positive therapeutic results it seems indicated to perform controlled comparative clinical trials.