[Factor analysis of the structure-activity relationship of di- and triphenylethylenes in 2 biochemical tests]

This paper deals with the study of biochemical activity, by means of correspondence analysis, of about fifty original molecules of di- and triphenylethylene structures. The pharmacological experiments were made on glutamate deshydrogenase and prostaglandine synthetase. A typology of several molecular groups is established and the effects of various substituents are specified.