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Published on: June 23, 2022
A clinical experience with the NCGT graft
Journal of Biomedical Materials Research
|May 1, 1981
Summary
Autogenous vein grafts remain superior for vascular reconstruction. However, modified collagen grafts (NCGT) offer a useful, non-thrombogenic alternative when veins are unavailable, providing prolonged patency.
Area of Science:
- Vascular Surgery
- Biomaterials Science
Background:
- Vascular reconstruction often relies on autogenous vein grafts.
- Alternative graft materials are needed for situations where veins are unavailable.
Purpose of the Study:
- To compare the patency rates of autogenous vein grafts, Johnson & Johnson dialdehyde-starch-tanned collagen prostheses, and NCGT grafts.
- To evaluate the efficacy of NCGT grafts as a non-thrombogenic alternative in vascular reconstruction.
Main Methods:
- A comparative study involving 130 grafts in 101 patients.
- Graft types included 47 veins, 25 Johnson & Johnson collagen prostheses, and 58 NCGT grafts.
- Follow-up period of 40 months.
Main Results:
- NCGT grafts demonstrated a cumulative patency of 73%, even with poor runoff.
- Venous bypasses showed superior patency rates compared to NCGT grafts.
- Modified collagen (NCGT) provides a useful, non-thrombogenic surface for prolonged patency.
Conclusions:
- Autogenous veins are the preferred conduit for vascular reconstruction.
- NCGT grafts are a valuable alternative when autogenous veins cannot be used.
- Modified collagen can serve as an effective prosthesis in vascular reconstruction.
