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[Gonadotropic regulation of androgen-producing ovarian tumors]
Abstract:
As a result of the study of the LH, FSH, prolactin and testosterone content in the blood of patients with androgen-producing ovarian tumors and LH-tumor tissue binding in vitro, it was detected that the gonadotropic hormone content may be low, normal and high. The testosterone level does not correlate with LH, FSH and prolactin concentration. LH-receptor binding is disturbed in the androgen-producing tumor tissue and hormone presence is not necessary to maintain androgen secretion by the tumor.