[The behavior of the thyrotropin-releasing hormone test in fasting with and without triiodothyronine administration]

It is reported on the performance of the 400 microgram TRH/TSH test in adipose persons in the course of a zero diet and on the effects of an application of 50 micrograms tri-iodothyronine during 7 days on the TRH/TSH test on the same conditions. During total fasting the basic and TRH-stimulating TSH-level shows a slight tendency of decrease, but scarcely significant changes. After application of 50 micrograms tri-iodothyronine an unequivocal suppression of the TSH-concentration in the serum is to be recognized. By these results and with the help of literary data by means of the most sensitive test of the diagnostics of hypothyroidism a general hypofunction of the pancreas could be excluded, as it was supposed in the low T3 syndrome. But tri-iodothyronine deficiency in some tissues is still discussed at present.