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Related Experiment Videos

Papillary renal cell carcinoma: ultrasonic/pathologic correlation.

C L Blei, D S Hartman, A C Friedman

    Journal of Clinical Ultrasound : JCU
    |November 1, 1982
    PubMed
    Summary

    Papillary renal cell carcinoma often appears hypoechoic on ultrasound, distinguishing it from other kidney cancers. This characteristic is frequently linked to cystic necrosis within the tumor.

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    Area of Science:

    • Nephrology
    • Radiology
    • Oncology

    Background:

    • Papillary renal cell carcinoma (PRCC) is a distinct subtype of kidney cancer.
    • Differentiating PRCC from nonpapillary renal cell carcinoma (NPRCC) is crucial for treatment and prognosis.
    • Ultrasound is a common imaging modality for renal masses.

    Purpose of the Study:

    • To investigate the ultrasound characteristics of papillary renal cell carcinoma.
    • To compare the sonographic patterns of PRCC with those of NPRCC.
    • To identify imaging features that may help distinguish between these two entities.

    Main Methods:

    • Retrospective analysis of 11 surgically confirmed cases of PRCC.
    • Retrospective review of 65 surgically confirmed cases of NPRCC.

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  • Correlation of ultrasound findings with gross pathology and clinicopathologic data.

    • Main Results:

    • 64% of PRCC cases exhibited hypoechogenicity (less echogenic than the renal cortex) on ultrasound.
    • Only 23% of NPRCC cases were hypoechoic.
    • Hypoechogenicity in PRCC was often associated with large central cystic necrosis.

    Conclusions:

    • Renal papillary carcinoma tends to present as a hypoechoic mass on ultrasound.
    • Hypoechogenicity on ultrasound may be a useful indicator for suspecting PRCC.
    • Cystic necrosis is a common finding contributing to the hypoechoic appearance of PRCC.