Related Experiment Video

Updated: Aug 18, 2026

Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging
12:58

Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging

Published on: October 24, 2010

[Criteria of the epidemiological surveillance of meningococcal infection]

N P Deviatkina, A A Demina, L I Larina

    Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
    |August 1, 1982
    PubMed

    Insights

    Serogroup A meningococci drive increased meningococcal disease morbidity. Monitoring circulating meningococcal serogroups in healthy populations is crucial for effective epidemiological surveillance and control of infection.

    Area of Science:

    • Epidemiology
    • Microbiology
    • Public Health

    Background:

    • Meningococcal infection poses a significant public health challenge.
    • Understanding the dynamics of meningococcal serogroups is vital for disease control.

    Purpose of the Study:

    • To analyze the role of different meningococcal serogroups in disease outbreaks.
    • To establish criteria for effective epidemiological surveillance of meningococcal infection.

    Main Methods:

    • Generalization of study results from eight regions using unified methods.
    • Analysis of meningococcal serogroup composition in healthy populations.
    • Selective bacteriological surveys to identify circulating serogroups.

    Main Results:

    • Serogroup A meningococci identified as the primary driver of increased morbidity.
    • A correlation was found between morbidity levels and the serogroup composition of meningococci in healthy individuals.
    • The importance of targeted bacteriological surveys was demonstrated.

    Conclusions:

    • Serogroup A is the leading cause of meningococcal disease outbreaks.
    • Epidemiological surveillance systems must incorporate monitoring of meningococcal serogroups in healthy populations.
    • Specific criteria for surveillance are proposed to improve early detection and response.

    More Related Videos

    Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery10:03

    Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

    Published on: November 5, 2019

    Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Detection of Central Nervous System Pathogens10:08

    Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Detection of Central Nervous System Pathogens

    Published on: April 17, 2026

    Related Concept Videos

    Bacterial Meningitis01:24

    Bacterial Meningitis

    Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
    Viral Meningitis01:18

    Viral Meningitis

    Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
    Cryptococcal Meningitis01:27

    Cryptococcal Meningitis

    Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
    Bacterial Meningitis I: Introduction01:22

    Bacterial Meningitis I: Introduction

    Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
    Bacterial Meningitis II: Pathophysiology01:26

    Bacterial Meningitis II: Pathophysiology

    Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...