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Abstract:
The effectiveness and safety of different methods of radioimmunoassay to determine the thyroid function were studied in 298 patients: 172 with nodose toxic goiter and 116 with nodose euthyroid goiter. A "warm", "hot", "cold" and "autonomic" nodes, respectively, prevailed in nodose goiter, on skanning. Free triiodothyronine index and elevated serum triiodothyronine index (EST3I) were calculated to determine the effect of thyroxin-binding ability of globulin on the total triiodothyronine level. Three types of thyrotoxicosis (T3/4-, T3- and T4-thyrotoxicosis) were found as a result of using complex methods to record the tests, showing a functional state of the hypophyseal-thyroid system. A high informativeness of the main thyroid tests was detected, i.e. determination of the total thyroxin, serum triiodothyronine and thyroxin efficiency coefficient. EST3I has the most diagnostic significance, being especially valuable in T3-thyrotoxicosis detection.