Related Experiment Video
Updated: Aug 17, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Tuberculous peritonitis in patients undergoing chronic home peritoneal dialysis
Abstract:
Peritonitis is a well-recognized complication of chronic peritoneal dialysis. However, in many instances the etiology of the peritonitis remains obscure despite intensive evaluation. Recent reports have suggested that pulmonary and extrapulmonary tuberculosis occurs with increased incidence in chronic hemodialysis patients. We report the first three cases of tuberculous peritonitis occurring in patients being treated with chronic intermittent peritoneal dialysis. The lack of active tuberculosis elsewhere and the predominance of polymorphonuclear leukocytes in peritoneal fluid made the diagnosis particularly difficult in this setting. The characteristics of the peritoneal fluid are quite similar to that seen in bacterial peritonitis, and unlike that found in peritonitis due to tuberculosis in nondialyzed patients. Tuberculous peritonitis should be suspected in peritoneal dialysis patients with chronic or relapsing peritonitis in whom the diagnosis of bacterial or fungal peritonitis cannot be confirmed.
Insights
Tuberculous peritonitis is a difficult diagnosis in patients undergoing chronic peritoneal dialysis. Its symptoms mimic bacterial peritonitis, complicating identification and treatment.
Area of Science:
- Nephrology
- Infectious Diseases
- Microbiology
Background:
- Peritonitis is a common complication of chronic peritoneal dialysis (CPD).
- The cause of peritonitis is often unclear despite thorough investigation.
- Tuberculosis (TB) incidence is rising in hemodialysis patients.
Observation:
- This study presents three cases of tuberculous peritonitis in patients on CPD.
- Diagnosis was challenging due to absent signs of active TB and peritoneal fluid rich in polymorphonuclear leukocytes.
- Peritoneal fluid analysis resembled bacterial peritonitis, differing from TB peritonitis in non-dialysis patients.
Findings:
- Tuberculous peritonitis can occur in patients undergoing chronic intermittent peritoneal dialysis.
- Diagnostic indicators in peritoneal fluid may be misleading, mimicking bacterial peritonitis.
- Early suspicion is crucial for patients with persistent or recurrent peritonitis.
Implications:
- Clinicians should consider tuberculous peritonitis in CPD patients with unexplained chronic or relapsing peritonitis.
- This highlights the need for specific diagnostic approaches for TB in dialysis patients.
- Timely diagnosis and treatment are essential to prevent complications in this vulnerable population.
Related Concept Videos
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Peritoneal Dialysis I: Introduction and Procedure
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis III: Nursing Management

