[Evaluation of sinoatrial conduction time by recording the sinus node potential. Comparison with indirect methods of...

A method of recording the sinus node potential (SNP) has recently been introduced in clinical electrophysiology. The sinoatrial conduction time can now be measured directly (SACTD) as the interval between the onset of the SNP and the onset of atrial activation. We measured the SACTD in 16 normal subjects and in 7 patients with sinus node dysfunction. These values were compared with those obtained by the indirect methods of Strauss et al (SACTS) and Narula et al (SACTN). In normal subjects the SACTD ranged from 50 to 130 ms (average 84,4 +/- 22,35); the SACTS, from 55 to 160 ms (92,9 +/- 29,3), and the SACTN from 70 to 175 ms (113,2 +/- 28,8). In patients with sinus node dysfunction the SACTD ranged from 200 to 290 ms (227 +/- 32,5), the SACTS, from 52 to 198 ms (111,8 +/- 59,3) and the SACTN from 89 to 251 ms (142,3 +/- 63). No significant difference was observed between normal and pathological subjects using the indirect methods of evaluation. However, the SACTD method showed a very significant difference between the two groups (p less than 0,0005) with no overlap. No correlations were observed between the values obtained by the indirect and direct methods of measuring SACT.