Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serial synapses in Aplysia.

K Graubard

    Journal of Neurobiology
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Serial synapses, identified in the Aplysia abdominal ganglion, feature unique structural characteristics. These findings suggest a potential anatomical basis for complex neural processes like presynaptic inhibition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tiling of the body wall by multidendritic sensory neurons in Manduca sexta.

    The Journal of comparative neurology·2001
    Same author

    Neural network partitioning by NO and cGMP.

    The Journal of neuroscience : the official journal of the Society for Neuroscience·2001
    Same author

    Molecular underpinnings of motor pattern generation: differential targeting of shal and shaker in the pyloric motor system.

    The Journal of neuroscience : the official journal of the Society for Neuroscience·2000
    Same author

    Pharmacologically and functionally distinct calcium currents of stomatogastric neurons.

    Journal of neurophysiology·1998
    Same author

    The NO/cGMP pathway and the development of neural networks in postembryonic lobsters.

    Journal of neurobiology·1998
    Same author

    Organization of the stomatogastric neuropil of the crab, Cancer borealis, as revealed by modulator immunocytochemistry.

    Cell and tissue research·1997
    Same journal

    The molecular receptive range of an olfactory receptor in vivo (Drosophila melanogaster Or22a).

    Journal of neurobiology·2006
    Same journal

    Consistent dynamics suggests tight regulation of biophysical parameters in a small network of bursting neurons.

    Journal of neurobiology·2006
    Same journal

    Early condition, song learning, and the volume of song brain nuclei in the zebra finch (Taeniopygia guttata).

    Journal of neurobiology·2006
    Same journal

    L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord.

    Journal of neurobiology·2006
    Same journal

    Singing, but not seizure, induces synaptotagmin IV in zebra finch song circuit nuclei.

    Journal of neurobiology·2006
    Same journal

    Developmental regulation of sensory axon regeneration in the absence of growth cones.

    Journal of neurobiology·2006
    See all related articles

    Area of Science:

    • Neuroscience
    • Cell Biology
    • Electron Microscopy

    Background:

    • Serial synapses are a specialized neuronal junction.
    • Understanding their structure is key to deciphering neural circuit function.

    Purpose of the Study:

    • To characterize the ultrastructure of serial synapses in the Aplysia abdominal ganglion.
    • To explore the potential functional implications of these synaptic arrangements.

    Main Methods:

    • Transmission electron microscopy was employed.
    • Ultrathin sections of the Aplysia abdominal ganglion neuropil were analyzed.
    • Synapses were identified and characterized based on morphological features.

    Main Results:

    • A specific class of serial synapses was identified, characterized by clustered synaptic vesicles, widened extracellular space with electron-dense material, and lack of postsynaptic specialization.

    Related Experiment Videos

  • These synapses occurred between small neuronal profiles (1-3 micrometer diameter).
  • Approximately 40% of postsynaptic profiles contained vesicles similar to presynaptic ones.

    • Conclusions:

    • The identified serial synapses possess distinct ultrastructural features.
    • These structures may serve as the anatomical substrate for presynaptic inhibition, facilitation, and dishabituation in Aplysia.
    • Further research is warranted to confirm the functional role of these serial synapses.