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Related Experiment Videos

[Long-term treatment with Des-Phe-Insulin].

S Hirn, H Pietschmann

    Wiener Klinische Wochenschrift
    |December 24, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Des-phe-insulin (DPI) offers flexible, effective long-term therapy for insulin-dependent diabetics, including managing emergencies, with no observed side effects requiring treatment interruption.

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    Area of Science:

    • Endocrinology
    • Pharmacology

    Context:

    • Geriatric department setting
    • Long-term study (up to 6 years)
    • Treatment of 61 insulin-dependent diabetics

    Purpose:

    • Evaluate the efficacy and safety of des-phe-insulin (DPI) for long-term diabetes management
    • Assess flexibility in therapy options (pure, amorphous, mixed DPI)
    • Investigate management of metabolic emergencies with DPI

    Summary:

    • Des-phe-insulin (DPI) demonstrated flexible and effective long-term therapeutic use in 61 insulin-dependent diabetics.
    • Therapy options included pure DPI, amorphous DPI, or mixed formulations, allowing adaptable patient management.
    • No significant differences in insulin dosage efficacy were noted compared to other insulin preparations, and no severe side effects necessitated treatment cessation.

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    Impact:

    • Highlights DPI as a viable option for long-term insulin therapy in geriatric patients.
    • Suggests DPI's utility in managing both routine diabetes care and acute metabolic situations.
    • Supports the safety profile of DPI for extended use in diabetic patients.