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Comparison of acquired monosaccharide intolerance and acute diarrheal syndrome

F Jalili, E O Smith, V N Nichols

    Journal of Pediatric Gastroenterology and Nutrition
    |January 1, 1982
    PubMed

    Insights

    Nine percent of diarrhea admissions had acquired monosaccharide intolerance (AMI). Malnutrition was a key factor in AMI development, suggesting a nutritional insult occurred before hospital admission.

    Area of Science:

    • Pediatric Gastroenterology
    • Nutritional Science

    Background:

    • Diarrhea is a common reason for hospital admission in children.
    • Acquired monosaccharide intolerance (AMI) is a potential complication of diarrheal illness.
    • Acute diarrheal syndrome (ADS) serves as a comparator for AMI outcomes.

    Purpose of the Study:

    • To compare the clinical course of acquired monosaccharide intolerance (AMI) with acute diarrheal syndrome (ADS).
    • To identify factors contributing to the development of AMI in hospitalized pediatric patients.

    Main Methods:

    • Retrospective study design.
    • Analysis of hospital admission data for diarrhea at Ben Taub General Hospital.
    • Comparison of patient demographics, birth characteristics, and nutritional status between AMI and ADS groups.

    Main Results:

    • Nine percent of diarrhea admissions were diagnosed with AMI.
    • Patients with AMI were younger at admission compared to ADS patients.
    • Malnutrition was significantly more prevalent in AMI patients (p < 0.02), despite similar birthweights and prematurity rates.

    Conclusions:

    • Malnutrition is a significant contributing factor to the development of acquired monosaccharide intolerance.
    • Nutritional insult likely occurs between birth and hospital admission in children who develop AMI.
    • Early identification and management of malnutrition may be crucial in preventing or mitigating AMI.

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