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Updated: Aug 15, 2026

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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Application of prosthetics to anterior cruciate ligament reconstruction and repair
Clinical Orthopaedics and Related Research
|January 1, 1983
Abstract:
The evolution of synthetic materials to aid in the repair of anterior cruciate ligament (ACL) instability is in an embryonic stage of development. After 12 years of animal and clinical trials, progress is emerging from synthetic augmentation rather than synthetic replacement. Synthetic materials are being given the strictest tests of purity, strength, and biologic tolerance by engineering and animal laboratories in preparation for controlled human trial.

