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High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
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Killing of blood-stage murine malaria parasites by hydrogen peroxide

H M Dockrell, J H Playfair

    Infection and Immunity
    |January 1, 1983
    PubMed

    Abstract:

    Both nonlethal Plasmodium yoelii and lethal Plasmodium berghei were killed in vitro by hydrogen peroxide at concentrations as low as 10(-5) M. Higher concentrations were required in the presence of added normal erythrocytes. Injection of hydrogen peroxide in vivo significantly reduced P. yoelii parasitemia but had less effect on P. berghei.

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