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Related Experiment Videos

Phenothiazine induced lingual trauma.

A W Miglets, G Racey, J L Hoffer

    The Laryngoscope
    |January 1, 1983
    PubMed
    Summary

    Phenothiazine drugs can cause rare but severe complications, including tongue protrusion and mastication muscle spasms. This case highlights a critical airway and management challenge due to tongue entrapment and edema.

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    Area of Science:

    • Pharmacology
    • Neurology
    • Emergency Medicine

    Background:

    • Phenothiazines are antipsychotic medications with known neurological side effects.
    • Extrapyramidal symptoms, such as dystonia, are common adverse effects.

    Observation:

    • A 34-year-old woman developed complications from phenothiazine use.
    • She experienced rhythmic tongue protrusion, which became trapped by mastication muscle spasms.
    • This led to significant tongue edema and compromised viability.

    Findings:

    • The patient presented a complex airway management problem.
    • Therapeutic interventions were challenging due to the drug-induced complications.

    Implications:

    • This case underscores the importance of recognizing rare phenothiazine side effects.
    • It highlights the need for prompt and specialized management of drug-induced emergencies.
    • Awareness of such complications is crucial for clinicians managing patients on phenothiazines.

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